US domestic-20ml Estradiol Valerate (EV,Ediol V) 10mg/ml 
1 vial--132#
9668 in stock
PPL U.S. domestic -> Injectables
Product number:32482
20ml Estradiol Valerate (EV,Ediol V) 10mg/ml 
US$ 40.0
Quantity units

Estradiol valerate (EV), It is used in hormone therapy for menopausal symptoms and low estrogen levels, hormone therapy for transgender people, and in hormonal birth control. It is also used in the treatment of prostate cancer. The medication is taken by mouth or by injection into muscle or fat once every 1 to 4 weeks.

Side effects of estradiol valerate include breast tenderness, breast enlargement, nausea, headache, and fluid retention. Estradiol valerate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. It is an estrogen ester and a prodrug of estradiol in the body.Because of this, it is considered to be a natural and bioidentical form of estrogen.

Estradiol valerate was first described in 1940 and was introduced for medical use in 1954.[18][19][20] Along with estradiol cypionate, it is one of the most widely used esters of estradiol.Estradiol valerate is used in the United States, Canada, Europe, and throughout much of the rest of the world.It is available as a generic medication.


Estradiol valerate is a medication commonly used in hormone replacement therapy (HRT) for transgender women, also known as male-to-female (MTF) individuals. It is a form of estrogen, specifically estradiol, which is the primary female sex hormone. Estradiol valerate is administered to help feminize the body and induce the physical changes associated with female secondary sexual characteristics.

 Purpose: Estradiol valerate is used to increase the levels of estrogen in the body. Estrogen is responsible for developing and maintaining female secondary sexual characteristics such as breast growth, redistribution of body fat, softer skin, and decreased body hair.

 Dosage: The dosage of estradiol valerate can vary depending on individual needs and hormone levels. The initial dosage is typically low and gradually increased over time to achieve the desired effects. Dosage adjustments may be made based on regular blood tests to monitor hormone levels and overall health.

Side Effects: Like any medication, estradiol valerate can have potential side effects. These may include breast tenderness, mood swings, changes in libido, weight fluctuations, and mild fluid retention. It is important to discuss any side effects with your healthcare provider, as they can provide guidance and support.